Muffy is the name of three female characters on Married... with Children and could refer to:
- Muffy (Season 3) - Sales associate at Francine's of Hollywood in the season 3 episode, "Her Cups Runneth Over"
- Muffy (Season 4) - Actress in the Dr. Shoe commercial in the season 4 episode, "976-SHOE"
- Muffy (Season 7) - News reporter in the season 7 episode "Chicago Wine Party"